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NUVIGIL tablets contain 50, 150 or 250 mg of armodafinil and the following inactive ingredients: croscarmellose sodium, lactose monohydrate, magnesium stearate, microcrystalline cellulose, povidone, and pregelatinized CLINICAL PHARMACOLOGY Mechanism of Action nuvigil nausea nuvigil half life nuvigil zoloft nuvigil mg nuvigil high nuvigil vs provigil nuvigil and Pharmacology The precise mechanism(s) through which armodafinil (R-enantiomer) or modafinil (mixture of R- and S-enantiomers) promote wakefulness is unknown .
Both armodafinil and modafinil have shown similar pharmacological properties in nonclinical animal and in vitro studies, to the extent At pharmacologically relevant concentrations, armodafinil does not bind to or inhibit several receptors and enzymes potentially relevant for sleep/wake regulation, including those for serotonin, dopamine, adenosine, galanin, melatonin, melanocortin, orexin-1, orphanin, PACAP PI + MG October 2010 or benzodiazepines, or transporters for GABA, serotonin, norepinephrine, and choline or phosphodiesterase VI, COMT, nuvigil GABA transaminase, and tyrosine hydroxylase .
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